"Advanced One is the first multiple to combine the convenience of a once-a-day with formulation that reflects the advancements in nutritional science. The expert formulators at Source Naturals designed Advanced One to combine high levels of vitamins and minerals with protective nutraceuticals, based on the latest scientific research. Advanced One includes special ingredients such as the ""core four"" - N-acetyl cysteine, lipoic acid, silymarin and coenzyme Q10 - for nutrient activation, anti-aging antioxidant protection and nonstimulant energizing.nutraceuticals, based on the latest scientific research."