Hyaluronic acid Hyaluronan, HA , is a linear polysaccharide composed of repeating disaccharide units of N-acetyl-flucosamine and D-glucuronic acid. HA occurs in the soft connective tissues of the body, especially in the fluids around the joints, and as a cementing agent in the subcutaneous tissue. HA is naturally distributed throughout the human body where, among other noteworthy properties, it holds water in the extracellular matrix of dermal and joint connective tissue, contributing to joint lubrication and elasticity of the skin. As we age, HA content in our body diminishes, resulting in a loss of viscoelasticity in the tissue that manifests itself visibly in wrinkles and physically in joint pain. Test results indicate that the next generation of functional HA-supplements is very promising. HA is classified as a food and is completely safe, effective, and easy to take as a dietary supplement.