For adults, take two 2 tablets three times daily, or six 6 tablets at night before retiring.
Not for use by persons with high blood pressure, diabetes, liver, gastrointestinal or kidney disorders, pregnant or lactating women, or persons under the age of 18. Do not exceed recommended dosage. Do not use if you have or develop diarrhea, loose stools, or abdominal pain because Cascara Sagrada and Senna may worsen these conditions and be harmful to your health. KEEP OUT OF REACH OF CHILDREN.